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Shoulder, wrist, and hand orthotic devices are commonly used in post-stroke rehabilitation, yet no existing device integrates both shoulder and hand support. Additionally, most rehabilitation tools focus on spasticity rather than flaccid paralysis. This study aimed to develop a dynamic upper limb orthosis for post-stroke neuro-flaccid patients to enhance neuroplasticity, improving motor function, muscle tone, and grip strength. Over a year, participants used the device during physiotherapy sessions for three months. Results showed significant improvements in motor function, joint mobility, and muscle tone, though grip strength remained unchanged. This innovative orthosis offers a promising solution for post-stroke rehabilitation.