Virtual Booth

Malaria is caused by parasites. MSP1 and EMP1 play a critical role in the parasite's ability to invade human red blood cells. Designing CRISPR/Cas9 gene knockout strategy to target these proteins is crucial and important to reduce infection of malaria by prevent these proteins to bind to human red blood cells. In conclusion, the study successfully identified a few potential gRNA targets. The selected gRNAs demonstrated the ability to induce specific DNA cleavage, crucial for achieving an effective gene knockout. A novel tool for malaria control by disrupting the gene-mediated invasion of human red blood cells and reducing disease transmission.