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ArtoLips is a revolutionary natural lipstick infused with Artocarpin, extracted from the trunk of Artocarpus heterophyllus. Unlike conventional lip care products, which contain synthetic chemicals and preservatives, ArtoLips offers therapeutic benefits. Our study showed that Artocarpin exhibited the highest cytotoxicity against cancer stem cells (CSCs) with an IC50 value of 5.07 microgram per mililiters and disrupted CSC multipotency by altering adipogenic, osteogenic, and chondrogenic differentiation.ArtoLips provides aesthetic enhancement along with free radical protection, regenerative, and anti-inflammatory benefits. By using sustainable, plant-based ingredients, ArtoLips sets a new standard for eco-friendly, bioactive cosmetics.